What can be done about those moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouthshutterstock_134597612 (nasolabial folds)? And can anything restore your lips to their previous fullness? Restylane can be a great option.

About Restylane

Restylane is an FDA-approved dermal filler made of a biodegradable, non-animal stabilized hyaluronic acid. Hyaluronic acid is a natural substance found in all living organisms and provides volume and fullness to the skin.

Restylane is formulated as a clear gel and uses a dual mechanism of action to help correct moderate to severe wrinkles and folds. Upon being injected beneath the skin’s surface, Restylane gel integrates into dermal tissue then attracts and binds to water molecules to help maintain volume. Restylane is gradually degraded by the body’s own mechanism and disappears without any residue.

Results can be seen immediately following Restylane treatment and last for up to six months. Some patients may achieve results that last longer than six months, depending upon injection site.

Restylane does not require any allergy or skin test prior to injection. Restylane is also marketed and sold in more than 65 countries outside the United States where it has been usRestylane Reveal Apped in more than ten million procedures.


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Frequently Asked Questions

Where else can Restylane be injected?

• Restylane is intended for the face and lips only.
• Safety in anatomic regions other than nasolabial folds or lips have not been established.
• Restylane must not be implanted into blood vessels

How much Restylane can be injected in a single treatment?

• Based on U.S. clinical studies, patients should be limited to 6 mL per patient per treatment in wrinkles and folds such as the nasolabial folds and to 1.5 mL per lip per treatment. The safety of injecting greater amounts has not been established.

Who cannot have Restylane injections?

• Patients with severe allergies, including allergies to gram positive bacterial proteins
• Patients with bleeding disorders
• It is recommended that Restylane should not be used at sites in which an active inflammatory process (skin eruptions such as cysts, pimples, rashes, or hives) or infection is present
• Safety of Restylane in pregnancy, breastfeeding, or patients under 18 years is not established. Safety and efficacy for lip augmentation in patients under 21 years is not established.
• Formations of keloids may occur after dermal filler injections, but keloids were not observed in Restylane clinical trials in 430 patients.
• Restylane injection may cause hyperpigmentation of the skin at the injection site. In African-American subjects, the incidence of post-inflammatory hyperpigmentation was nine percent, and in 50 percent the events lasted up to six weeks after initial implantation. Swelling may occur more frequently in subjects of color receiving lip augmentation.
• Restylane should be used with caution in patients on immunosuppressive therapy.

Does Restylane have any side effects?

Adverse effects when injected in the face may include:

• Bruising
• Redness
• Swelling
• Pain/Soreness
• Tenderness
• Itching
• Hyperpigmentation
• Injection site scabbing
• Infection
• Hardness/Nodule

When injected into the lips, side effects may include:

• Redness
• Swelling
• Pain/Soreness
• Tenderness
• Bruising
• Itching
• Headache
• Skin Exfoliation