Restylane® Refyne & Defyne

Over time, consistent facial movement can cause unwanted smile and laugh lines. Restylane® Refyne and Restylane® Defyne are meant to soften the appearance of nasolabial folds and marionette lines on the face.

What are Restylane® Refyne and Restylane® Defyne?

Both Restylane® Refyne and Defyne are hyaluronic acid fillers created to soften smile and laugh lines in patients 21 years and older. The difference between the two is the degree of lines that they treat; Restylane® Refyne treats mild to moderate facial lines and folds, while Restylane® Defyne treats moderate to severe lines and folds.

Both fillers are created using XpresHAn Technology, which creates a gel consistency that is flexible, allowing for the fillers to move with the face for a natural appearance. This means patients can expect to see a soft, natural difference instead of stiff, unnatural-looking results.

Am I a Candidate?

Patients who are unhappy with the appearance of mild to severe nasolabial folds and marionette lines can often benefit from these fillers in Orlando. Patients who have a history of severe allergies, bleeding disorders, or women who are pregnant or breastfeeding should not receive these injections.

How Long Do Results Last?

Both Restylane® Refyne and Defyne can last up to 12 months. A plastic surgery consultation in Orlando is needed to help determine if these fillers are right for you.


After receiving injections, patients may experience itching, swelling, bruising, redness, or soreness around the injection site. These side-effects are often mild and should resolve within a couple days. Makeup can often be used to conceal any redness that occurs.

If you are interested in Restylane® Refyne or Restylane ® Defyne in Lake Mary or Orlando, contact Orlando Plastic Surgery Associates today to schedule a consultation.

Patients interested in Restylane® in Orlando may be interested in Restylane® Silk or Restylane® Lyft.